Investigation on preliminary phytochemical and in-vitro anti cancer activity of leaves of Delonix regia by MTT assay on Hela–Human cervix and HT-29-Human Colorectal Adenocarcinoma. The powdered leaves were subjected for the proximate analysis in which studies were carried out related to ash values, extractive values, fluorescence analysis and preliminary phytochemical screening. Major extraction was carried out by simple maceration method using ethanol as solvent. The in-vitro anti-cancer activity of leaves Delonix regia was evaluated in-vitro by MTT assay on Hela-Human cervix and HT-29-Human colorectal adenocarcinoma. A greenish solid matter of 4.53 % w/w was obtained from the dried leaves powder. Administration of ethanolic extract of Delonix regia leaves produced a significant anti-cancer activity and the IC50 value was found to be 95.11 μg/ml for HeLa cell and 73.09 μg/ml for HT-29 cell lines. In conclusion, administration of ethanolic extract of Delonix regia leaves produced a significant anti-cancer activity and IC50 value was found to be 95.11 μg/ml for HeLa cell and 73.09 μg/ml for HT-29 cell lines. The present work justifying the folklore claim of the Delonix regia leaves for treatment of different types of cancer.
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